Raymond Purves Bone & Joint Research Laboratory

The Raymond Purves Bone and Joint Research Laboratory leads Australia in research into some of the key musculoskeletal diseases affecting our population. This includes osteoarthritis, tendon injury and intervertebral disc degeneration.

There is currently no cure for these common, chronic disabling conditions and long-term management options are limited. It is only through a better understanding of the disease and tissue breakdown, that we will be able to develop therapies to modify the conditions.

The Raymond Purves Bone and Joint Research Laboratory team is well placed to improve the health of patients with musculoskeletal disease. We are located alongside Royal North Shore Hospital and have developed close relationships with orthopaedic surgeons and rheumatologists at the hospital. This means our latest research developments can be efficiently incorporated into future clinical care.


Professor Christopher Little Professor Christopher Little

Director Raymond Purves Bone and Joint Research Labs
Surgery, Faculty of Medicine and Health, Northern Clinical School
Kolling Institute
Institute of Bone & Joint Research
Member of the Charles Perkins Centre

 Dr Jiao Jiao Li

NHMRC Peter Doherty Biomedical Early Career Fellow

 Dr Cindy Shu

Postdoctoral Scientist

 Dr Sanaa Zaki

Postdoctoral Scientist

Dr James Melrose

Honorary Senior Research Fellow

Dr Margaret Smith

Honorary Research Fellow







Daniel Burkhardt - Research Officer

Yolanda Liu - Research Assistant

Susan Smith - Technical Officer

Dr Patrick Haubruck - PhD Student 

Dr Matthew McCann - MD Research Student

Sidharth Aravind - Placement Student

Vivian Shang - Honours Student

Developing regenerative therapies for osteoarthritis – To investigate the interactions between stem cells and diseased joint cells, and build on this knowledge to develop new ways of treating osteoarthritis

Developing new implants for musculoskeletal tissue repair – To develop and test tissue engineered methods of repairing musculoskeletal tissues including bones and joints

Events, News and Seminars

Researchers partner with industry for innovative study into osteoarthritis

Researchers partner with industry for innovative study into osteoarthritis

Regeneus, a clinical-stage regenerative medicine company, has announced an exciting research collabo..... Read more

Category: Musculoskeletal Research, Research Excellence

Expertise at the Kolling recognised

Expertise at the Kolling recognised

Congratulations to Professor David Hunter who’s been announced as a finalist for Research Australia’..... Read more

Category: Awards, Musculoskeletal Research

Research directs spotlight onto the effectiveness of spinal surgery

Research directs spotlight onto the effectiveness of spinal surgery

New research has found that while the majority of Australian spinal surgeons expect large improvemen..... Read more

Category: Musculoskeletal Research, Research Excellence