Raymond Purves Bone & Joint Research Laboratory

The Raymond Purves Bone and Joint Research Laboratory leads Australia in research into some of the key musculoskeletal diseases affecting our population. This includes osteoarthritis, tendon injury and intervertebral disc degeneration.

There is currently no cure for these common, chronic disabling conditions and long-term management options are limited. It is only through a better understanding of the disease and tissue breakdown, that we will be able to develop therapies to modify the conditions.

The Raymond Purves Bone and Joint Research Laboratory team is well placed to improve the health of patients with musculoskeletal disease. We are located alongside Royal North Shore Hospital and have developed close relationships with orthopaedic surgeons and rheumatologists at the hospital. This means our latest research developments can be efficiently incorporated into future clinical care.


Professor Christopher Little Professor Christopher Little

Director Raymond Purves Bone and Joint Research Labs
Surgery, Faculty of Medicine and Health, Northern Clinical School
Kolling Institute
Institute of Bone & Joint Research
Member of the Charles Perkins Centre

 Dr Jiao Jiao Li

Honorary Associate

 Dr Cindy Shu

Postdoctoral Scientist

 A/Professor Sanaa Zaki

Postdoctoral Scientist

Dr James Melrose

Honorary Senior Research Fellow

Dr Margaret Smith

Honorary Research Fellow


Daniel Burkhardt - Research Officer

Yolanda Liu - Research Assistant

Susan Smith - Technical Officer

Wenjie Yang – PhD student 

Dr Patrick Haubruck - PhD Student 

Sasha Gonzalez-Malcolm - Honours Student

Timothy Doran – Honours student

Yuhe (Chelsea) Mao – Honours student

Jiarong (Devina) Li – Honours student

Developing regenerative therapies for osteoarthritis – To investigate the interactions between stem cells and diseased joint cells, and build on this knowledge to develop new ways of treating osteoarthritis

Developing new implants for musculoskeletal tissue repair – To develop and test tissue engineered methods of repairing musculoskeletal tissues including bones and joints

Raymond Purves Bone & Joint Research Laboratory related information

Events, News and Seminars

Championing precision medicine for children living with arthritis

Championing precision medicine for children living with arthritis

The largest study in Australia into the treatment of juvenile arthritis may pave the way for a uniqu..... Read more

Category: Funding support, Musculoskeletal Research

Back pain treatments shouldn’t neglect the mind

Back pain treatments shouldn’t neglect the mind

New research by a team from the Kolling Institute has found the best treatment for chronic low back ..... Read more

Category: Musculoskeletal Research, Neuroscience and Pain Research, Research Excellence

Kolling researcher to join prestigious Harvard Medical School program

Kolling researcher to join prestigious Harvard Medical School program

Congratulations to Kolling Institute researcher Dr Manasi Mittinty who has been selected for the Adv..... Read more

Category: Musculoskeletal Research, Neuroscience and Pain Research