The Cancer Genetics Laboratory studies cancers of endocrine organs, many of which develop as a result of hereditary syndromes.
Our research team has expertise in cancer biology, diagnostic genetic testing, family counselling and targeted surveillance programs.
Our research translates discoveries in genetic research to improved clinical care for patients with endocrine cancers.
Head, Cancer Genetics Laboratory
Head, Department of Endocrinology, Royal North Shore Hospital
Co-Head, Cancer Genetics Laboratory
Co-Head, Cancer Genetics Laboratory
Senior Research Scientist
Research Fellow
Kolling Institute, Northern Clinical School
Scientific Officer | NSW Health Service
Senior Research Fellow | Northern Clinical School, University of Sydney
Visiting Scholar | University of Technology Sydney
Co-Chair |RNSH Institutional Biosafety Committee
Senior Scientific Officer NSW Health Service
Our current research programs are:
We perform NATA-accredited genetic testing for Multiple Endocrine Neoplasia syndrome type 2, Hereditary Phaeochromocytoma/Paraganglioma syndromes, hereditary hyperparathyroidism disorders and hereditary thyroid disorders.
Studying hereditary mutations in key genes associated with phaeochromocytomas and paragangliomas. Our research has made several discoveries that link mitochondrial dysfunction with a predisposition to these and other cancers. These biomarker discoveries have been translated into routine pathology practice.
Studying tumour or hereditary DNA mutations that predispose people to thyroid cancers. Our ground breaking work has included discovery of fusion chromosomes in particular subtypes of thyroid cancer. It has also examined the role of the BRAF oncogene in cancer metastasis and the specific role of a thyroid developmental transcription factor FOXE1 with thyroid cancer predisposition, a finding that links disruption in an early developmental gene with cancer development in adult life.
In this program, we study the microRNA changes associated with the highly malignant cancer of the adrenal cortex.
Studying the genetic and epigenetic changes of pituitary neoplasms.
http://sydney.edu.au/medicine/people/academics/profiles/bruce.robinson.php#publications-by-year
http://sydney.edu.au/medicine/people/academics/profiles/stanley.sidhu.php#publications-by-year
http://sydney.edu.au/medicine/people/academics/profiles/trisha.dwight.php#publications-by-year
https://www.researchgate.net/scientific-contributions/39734001_Diana_E_Benn
https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004523157.23 (Martyn Bullock)
Posted on: 10 December, 2020
The Kolling’s Dr Amanda Hudson will lead an exciting pilot study after being awarded an innovation g..... Read more
Category: Funding support, Neuroscience and Pain Research
Posted on: 10 December, 2020
Congratulations to Kolling cancer researcher and Sydney Vital fellow Dr Yaser Hadi Gholami on being ..... Read more
Category: Funding support
Posted on: 16 June, 2020
Former Kolling Institute director Professor Rob Baxter received an Order of Australia medal in the Q..... Read more
Category: Awards