Bowel Cancer and Biomarker Research Lab

Bowel cancer, also known as colorectal cancer, is the second most common cancer in Australian men and women. It affects 1 in 13 people. It is also Australia’s second deadliest cancer, with over 5,000 people dying each year. Early detection through screening can improve survival rates, however further research is needed to help find cures and prevent the disease.

The Bowel Cancer and Biomarker Laboratory at the Kolling Institute uses advanced technologies to study the genes and proteins responsible for bowel cancers growing and spreading. Our aim is to use a patient’s own molecular information to understand the risk of bowel cancer developing and to guide treatment options. As part of our research, we are studying how to control bowel polyp growth, which are precursors to cancer. We are doing this through diet and chemotherapy drugs.


Lead

Department Head:

Mark-P-Molloy Prof Mark P. Molloy, PhD | Lawrence Penn Chair of Bowel Cancer Research

The University of Sydney | Northern Clinical School
Faculty of Medicine and Health
Honorary Professor | Dept. Molecular Sciences, Macquarie University
Secretary | Australasian Proteomics Society

Jun-Li Dr Jun Li PhD

Post Doctoral Research Fellow

team-Pascal-Steffen Dr Pascal Steffen MSc, PhD

The University of Sydney, Faculty of Medicine and Health Northern Clinical School, Kolling Institute
Position: Cancer Institute NSW Early Career Fellow

Dr-Matthew-O-Rourke Dr Matthew O’Rourke BSc, MSc, PhD

The University of Sydney | Northern Clinical School | Bowel Cancer & Biomarker Lab
Faculty of Medicine and Health
Visiting Scholar University of Technology Sydney
Elected Member NSW Royal Society

Current bowel cancer research focuses on:

  • Why and how some bowel polyps become cancers
  • Which bowel tumours are likely to spread
  • Molecular make-up of colorectal tumours
  • Early detection of disease recurrence

Our research is facilitated by specimens from clinical projects we run including:

  • Sydney 1000 bowel cancer study
  • IMAP Bowel polyp study

Bowel Cancer and Biomarker Research related information

Events, News and Seminars

International focus on our ovarian cancer research

International focus on our ovarian cancer research

In an exciting breakthrough, researchers from the Kolling Institute’s Bill Walsh Lab have identified..... Read more

Category: Research Excellence

Home grown ideas place physio in patients' hands

Home grown ideas place physio in patients' hands

New research is testing a new way to meet the rapidly growing demand for physiotherapy in our publi..... Read more

Category: New Treatment

Common medication may lower risk of “heartbreak”

Common medication may lower risk of “heartbreak”

RNSH cardiologist Professor Geoffrey Tofler has led a world-first study which found that common med..... Read more

Category: Research Excellence