Bowel Cancer and Biomarker Research Lab

Bowel cancer, also known as colorectal cancer, is the second most common cancer in Australian men and women. It affects 1 in 13 people. It is also Australia’s second deadliest cancer, with over 5,000 people dying each year. Early detection through screening can improve survival rates, however further research is needed to help find cures and prevent the disease.

The Bowel Cancer and Biomarker Laboratory at the Kolling Institute uses advanced technologies to study the genes and proteins responsible for bowel cancers growing and spreading. Our aim is to use a patient’s own molecular information to understand the risk of bowel cancer developing and to guide treatment options. As part of our research, we are studying how to control bowel polyp growth, which are precursors to cancer. We are doing this through diet and chemotherapy drugs.


Department Head:

Mark-P-Molloy Prof Mark P. Molloy, PhD | Lawrence Penn Chair of Bowel Cancer Research

The University of Sydney | Northern Clinical School
Faculty of Medicine and Health
Honorary Professor | Dept. Molecular Sciences, Macquarie University
Secretary | Australasian Proteomics Society

Jun-LiDr Jun Li PhD

Postdoctoral Research Fellow

Dr-Matthew-O-RourkeDr Matthew O’Rourke BSc, MSc, PhD

Postdoctoral researcher
Elected Member NSW Royal Society

Dr Binh Pham, PhD

Postdoctoral Scientist

Dr Benita Tse

Postdoctoral Scientist

Current bowel cancer research focuses on:

  • Why and how some bowel polyps become cancers
  • Which bowel tumours are likely to spread
  • Molecular make-up of colorectal tumours
  • Early detection of disease recurrence

Our research is facilitated by specimens from clinical projects we run including:

  • Sydney 1000 bowel cancer study
  • IMAP Bowel polyp study

Events, News and Seminars

Cancer expertise recognised

Cancer expertise recognised

The Kolling’s Dr Amanda Hudson will lead an exciting pilot study after being awarded an innovation g..... Read more

Category: Funding support, Neuroscience and Pain Research

New funding launches exciting project to detect cancer earlier

New funding launches exciting project to detect cancer earlier

Congratulations to Kolling cancer researcher and Sydney Vital fellow Dr Yaser Hadi Gholami on being ..... Read more

Category: Funding support

Congratulations Professor Rob Baxter

Congratulations Professor Rob Baxter

Former Kolling Institute director Professor Rob Baxter received an Order of Australia medal in the Q..... Read more

Category: Awards