Bill Walsh Translational Cancer Research Laboratory

The Bill Walsh Translational Cancer Research Laboratory is the research arm of the Medical Oncology Department at Royal North Shore Hospital. 

We focus on increasing our understanding of cancer biology and how cancer will behave. We are also working to identify better ways to diagnose cancer. 

Through our research we are improving cancer treatment and offering better outcomes for those with the disease. 

Professor Nick Pavlakis

Professor Nick Pavlakis

Co-head, Bill Walsh Translational Cancer Research Laboratory
Associate Professor
Faculty of Medicine and Health
The University of Sydney
Senior Staff Specialist, Dept of Medical Oncology
Royal North Shore Hospital

Professor Stephen Clarke

Professor Stephen Clarke

Co-head, Bill Walsh Translational Cancer Research Laboratory
Professor
Faculty of Medicine and Health
The University of Sydney
Senior Staff Specialist, Dept. Medical Oncology
Royal North Shore Hospital

Helen Wheeler

Associate Professor Helen Wheeler

Associate Professor
Faculty of Medicine and Health
The University of Sydney
Co-team lead, Bill Walsh Translational Cancer Research Laboratory
Senior Staff Specialist
Head Department of Medical Oncology, Royal North Shore Hospital
Co-Lead, Inflammation Flagship
Sydney Vital Translational Cancer Research Centre

Dr Emily Colvin BMedSc (Hons), PhD

Dr Emily Colvin

Bill Walsh Translational Cancer Research Laboratory
Lecturer
Faculty of Medicine and Health
The University of Sydney

Associate Professor Connie Diakos BSc(Hons), PhD, MBBS, FRACP, MRACI CChem

Associate Professor Connie Diakos

Co-Chair, Cancer
Bill Walsh Translational Cancer Research Laboratory
Conjoint Senior Lecturer
Faculty of Medicine and Health
The University of Sydney

Dr Amanda Hudson BSc (Hons), PhD

Dr Amanda Hudson

Research Fellow, Bill Walsh Translational Cancer Research Laboratory
Faculty of Medicine and Health
The University of Sydney

Shihani Stoner

Senior Project Officer

Sooin Byeon

Sooin Byeon

Research Assistant

Taymin du Toit-Thompson

Taymin du Toit-Thompson

PhD Student
Faculty of Medicine and Health
The University of Sydney

Farah Abu Al-Hial

Farah Abu Al-Hial

Research Officer

Nada Cheikh-Ali

Nada Cheikh-Ali

Clinical Researcher

Hasanthi De Silva

Senior Research Officer

Liz Millar

Liz Millar

Research Assistant

Sara Mokhtar

Sara Mokhtar

Research Assistant

Narjis Fatima

Narjis Fatima

Postdoctoral Research Associate

Hye Soo Lee

Hye Soo Lee

Medical Placement Student

Krishna Kotecha

Krishna Kotecha

PhD Student
Faculty of Medicine and Health
The University of Sydney

Joe Wei

Joe Wei

Researcher

Dr Alexander Yuile

Bill Walsh Translational Cancer Research Laboratory
Medical Oncologist
Royal North Shore Hospital

  1. Teaching an Old Drug New Tricks: Can we repurpose an old drug as a new brain cancer treatment? 
  2. The immuno-coagulome: an untapped pathway for new therapeutics in glioma 
  3. Investigating how glioblastoma tumours change over time to become resistant to treatment 
  4. Unravelling the tumour micro-environment to combat brain cancer 
  5. Laying the foundations for improved treatments for IDH-mutated glioma 
  6. The interaction between coagulation, angiogenesis and inflammatory pathways in glioblastoma 
  7. MHF Brain Cancer PACT: Mark Hughes Foundation Collaborative Brain Cancer Pre-clinical pipeline for Advancing Cancer Therapeutics 
  8. Development of non-invasive monitoring for brain tumour recurrence and treatment resistance 
  9. A new class of theranostics for malignant brain cancer 
  10. Radiosensitisation of high-grade gliomas by modulating glucose metabolism 
  11. New Horizons: Therapeutic applications for medicinal cannabis in the treatment of brain cancer 

  1. The role ofIinflammation in colorectal cancer 
  2. Identifying prognostic protein markers in colorectal cancer tumour 
  3. Exploring a new nanotechnology strategy for the neo-adjuvant treatment of colorectal cancer by photodynamic therapy and ionising radiation 

  1. Investigating patterns of drug resistance in ALK rearranged non-small cell lung cancer 
  2. Exploring methods to improve efficacy of immunotherapy in non-small cell lung cancer 
  3. Identification of biomarkers for non-small cell lung cancer 
  4. Chemotherapy resistance in non-small cell lung cancer 
  5. The exhaled breath condensate proteome: a promising source of biomarkers for lung cancer 

  1. Improved treatment for mesothelioma: Can cannabinoids address this unmet need? 

  1. The role of dual PET scans in understanding neuroendocrine tumour behaviour 
  2. Analysing PET scans for neuroendocrine tumours 

  1. Evaluation of lysyl oxidase inhibitors as a new treatment for ovarian cancer 
  2. Investigating the role of long non-coding RNA (ribonucleic acid) in the ovarian cancer microenvironment 
  3. Improving ovarian cancer treatment using nanoparticles 

  • Biomarker identification for pancreatic cancer diagnosis 
  • Biomarker identification for pancreatic cancer prognosis. 
  • Identification of new drug targets for pancreatic cancer treatment 
  • Understanding the role of tumour microenvironment in pancreatic cancer progression 
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