Murray Maxwell Biomechanics Laboratory

The Murray Maxwell Biomechanics Laboratory works at the interface of engineering, anatomy, and orthopaedic surgery.

We focus on improving the understanding and treatment of musculoskeletal injury and disease through rigorous biomechanical and anatomical investigation. Our research is strongly translational, with a particular emphasis on advancing orthopaedic surgery by evaluating and refining surgical techniques, improving graft and implant performance, and developing novel solutions including engineered tissues, sensors, and therapeutic approaches.

The laboratory is committed to delivering research that has clear clinical relevance. By generating high-quality evidence and innovative technologies, we aim to improve surgical precision, reduce complications, and enhance patient recovery and long-term outcomes.

Our work also supports clinicians in decision-making and contributes to the development of next-generation orthopaedic devices and therapies.

Our research benefits patients, healthcare systems, and industry partners by translating scientific insight into improved surgical care and practical innovations in musculoskeletal health

Lead

People

Collaborations

Projects

Associate Professor Elizabeth Clarke, PhD, BE (Mechanical Biomedical), BSc

Associate Professor Elizabeth Clarke

Director, Murray Maxwell Biomechanics Laboratory
Faculty of Medicine and Health, The University of Sydney

    Robotic Simulation to Improve Orthopaedic Implant Surgery

    We use robotic joint simulation to improve planning and decision-making in orthopaedic implant surgery, particularly joint replacement. By recreating clinically relevant joint movement in the laboratory, we assess how implant position, alignment, and surgical technique influence function and stability. The goal is to generate evidence that helps surgeons refine procedures, improve implant performance, and support better patient outcomes. This platform also creates opportunities for collaboration with clinicians and technology partners working to improve joint replacement care.

    Human Tissue Atlas for Improved Grafts and Tissue Replacements

    This project is building a high-quality, open-access evidence database on the structure and mechanical behaviour of human tendon, ligament, and cartilage. The aim is to support better graft selection, improve tissue replacement strategies, and guide the development of engineered solutions for musculoskeletal repair. By providing a stronger foundation for reconstruction and replacement, this work has relevance for surgical care, tissue engineering, regenerative medicine, and medical innovation. It also supports collaboration across research, healthcare, and industry focused on improving treatment options for patients

    Evaluating Fixation and Reconstruction Strategies for Surgical Care

    This research evaluates how commonly used fixation and reconstruction methods perform in the repair of injured bones, tendons, and ligaments. The laboratory studies approaches involving anchors, sutures, plates, screws, and wires to understand how they support stability, strength, and surgical success. The aim is to generate evidence that can inform procedure choice, improve reconstruction strategies, and support the development of safer and more effective surgical devices. This work is directly relevant to clinicians, healthcare systems, and medical technology partners.

    Smart Sensors for Surgical Innovation and Translation

    This project explores sensor-based technologies that can provide better measurement and feedback during orthopaedic surgery and related musculoskeletal care. The aim is to support more informed surgical decision-making, improve precision, and help translate objective data into practical clinical use. By developing and evaluating new sensing approaches, the laboratory is contributing to innovation at the interface of surgery, engineering, and medical technology. This work has potential benefits for patients, clinicians, and industry partners developing the next generation of surgical tools and systems.

    Understanding the Long-Term Consequences of Joint Injury

    This work examines how joint injury can lead to ongoing mechanical changes that affect function, recovery, and the risk of later disease. The laboratory investigates how damage to cartilage, ligaments, and other joint structures may contribute to persistent symptoms, repeat injury, and osteoarthritis over time. The goal is to improve understanding of why some injuries have lasting consequences and to identify evidence that can guide prevention and treatment. This research has important implications for patients, clinicians, and health systems.

    Musculoskeletal Research

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