In the heart of the Kolling Institute, a world-renowned research centre, a raft of clinical trials is driving the future of healthcare.<\/p>\n\n\n\n
\n\u201cClinical trials are intrinsic to research,\u201d says Professor James Elliott, Academic Director of the institute. \u201cThey help us test something so that we can better inform care for patients with various conditions who come to our hospitals for treatment.\u201d<\/p>\n<\/blockquote>\n\n\n\n
The Kolling Institute has a strong track record in conducting impactful clinical trials. Notably, it has been involved in running multiple trials for those with heart and kidney disease, musculoskeletal conditions and chronic pain.<\/p>\n\n\n\n
Their cancer trials have made significant contributions across various tumour streams, including pancreatic, haematological, breast, and bowel cancers.<\/p>\n\n\n\n
James emphasises that basic science, discovery and scientific innovation are embedded in the Kolling\u2019s over 100-year history.<\/p>\n\n\n\n
\n\u201cOften, it is those innovations from our basic science laboratories that ultimately inform the mechanisms by which trials are developed.\u201d<\/p>\n<\/blockquote>\n\n\n\n
James adds that understanding the ways diseases work allows researchers to target trials more precisely, leading to better patient outcomes.<\/p>\n\n\n\n
However, the need for trials sometimes outpaces scientific understanding.<\/p>\n\n\n\n
\n\u201cWe can\u2019t always wait for a full understanding of a disease,\u201d James notes. \u201cIn some cases, we must move forward with trials to push the needle on patient care, even as we continue to explore the underlying mechanisms.\u201d<\/p>\n<\/blockquote>\n\n\n\n
A key advantage for the institute is its proximity to one of Australia\u2019s largest tertiary hospitals, Royal North Shore Hospital. This connection provides access to a vast patient population, which is crucial for conducting large-scale clinical trials.<\/p>\n\n\n\n
\n\u201cWe serve over a million patients,\u201d says James, stressing the importance of their \u201ctrial as therapy\u201d culture. \u201cWe want patients to expect that they may be invited to participate in a clinical trial or research study as part of their care.\u201d<\/p>\n<\/blockquote>\n\n\n\n
The Kolling Institute is a world leader in researching osteoarthritis, musculoskeletal conditions, cancer, neuroscience and pain, and cardiac, cardiovascular and renal disorders. <\/p>\n","protected":false},"author":1,"featured_media":2418,"menu_order":0,"template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[],"research-group-tax":[],"primary-research-area":[],"class_list":["post-2417","news","type-news","status-publish","has-post-thumbnail","hentry"],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop.webp",550,380,false],"thumbnail":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop-150x150.webp",150,150,true],"medium":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop-300x207.webp",300,207,true],"medium_large":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop.webp",550,380,false],"large":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop.webp",550,380,false],"1536x1536":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop.webp",550,380,false],"2048x2048":["https:\/\/kollinginstitute.org.au\/staging\/wp-content\/uploads\/2025\/09\/thumb_Blog_0Y3A5771_w550_h380_fcrop.webp",550,380,false]},"uagb_author_info":{"display_name":"ict-wordpress-support@sydney.edu.au","author_link":"https:\/\/kollinginstitute.org.au\/staging\/author\/ict-wordpress-supportsydney-edu-au\/"},"uagb_comment_info":0,"uagb_excerpt":"In the heart of the Kolling Institute, a world-renowned research centre, a raft of clinical trials is driving the future of healthcare. \u201cClinical trials are intrinsic to research,\u201d says Professor James Elliott, Academic Director of the institute. \u201cThey help us test something so that we can better inform care for patients with various conditions who…","_links":{"self":[{"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/news\/2417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/news"}],"about":[{"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/types\/news"}],"author":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":1,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/news\/2417\/revisions"}],"predecessor-version":[{"id":5194,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/news\/2417\/revisions\/5194"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/media\/2418"}],"wp:attachment":[{"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/media?parent=2417"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/categories?post=2417"},{"taxonomy":"research-group-tax","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/research-group-tax?post=2417"},{"taxonomy":"primary-research-area","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/staging\/wp-json\/wp\/v2\/primary-research-area?post=2417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}