{"id":2674,"date":"2025-09-17T15:06:49","date_gmt":"2025-09-17T05:06:49","guid":{"rendered":"https:\/\/webdev.sydney.edu.au\/kolling\/research-group\/raymond-purves-bone-joint-research-laboratory\/"},"modified":"2026-03-04T14:37:27","modified_gmt":"2026-03-04T03:37:27","slug":"raymond-purves-bone-joint-research-laboratory","status":"publish","type":"research-group","link":"https:\/\/kollinginstitute.org.au\/news_demo\/research-group\/raymond-purves-bone-joint-research-laboratory\/","title":{"rendered":"Raymond Purves Bone &#038; Joint Research Laboratory"},"content":{"rendered":"\n<p>The Raymond Purves Bone and Joint Research Laboratory leads Australia in research into some of the key musculoskeletal diseases affecting our population. This includes osteoarthritis, tendon injury and intervertebral disc degeneration.<\/p>\n\n\n\n<p>There is currently no cure for these common, chronic disabling conditions and long-term management options are limited. It is only through a better understanding of the disease and tissue breakdown, that we will be able to develop therapies to modify the conditions.<\/p>\n\n\n\n<p>The Raymond Purves Bone and Joint Research Laboratory team is well placed to improve the health of patients with musculoskeletal disease. We are located alongside Royal North Shore Hospital and have developed close relationships with orthopaedic surgeons and rheumatologists at the hospital. This means our latest research developments can be efficiently incorporated into future clinical care.<\/p>\n\n\n\n<div style=\"border-style:none;border-width:0px;--etb-a-tab-btn-bg-color:#FFFFFF;--etb-a-tab-btn-text-color:#ab40a1;--etb-a-tab-btn-heading-color:#ffffff;--etb-a-tab-bt-style:none;--etb-a-tab-bt-width:0px;--etb-a-tab-br-style:none;--etb-a-tab-br-width:0px;--etb-a-tab-bb-style:none;--etb-a-tab-bb-width:0px;--etb-a-tab-bl-style:none;--etb-a-tab-bl-width:0px;--etb-h-tab-btn-bg-color:#ffffff;--etb-h-tab-btn-text-color:#000000;--etb-h-tab-btn-heading-color:#000000;--etb-h-tab-bt-style:none;--etb-h-tab-bt-width:0px;--etb-h-tab-br-style:none;--etb-h-tab-br-width:0px;--etb-h-tab-bb-style:none;--etb-h-tab-bb-width:0px;--etb-h-tab-bl-style:none;--etb-h-tab-bl-width:0px;--etb-scroll-arrows-icon-color:#ab40a1\" class=\"wp-block-easy-tabs-block-tabs has-active-etb-bg-color has-active-etb-text-color has-active-etb-heading-color has-active-etb-border has-hover-etb-bg-color 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loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_lead-icon2.png\" alt=\"\" class=\"wp-image-1098\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Lead<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_people-icon2.png\" alt=\"\" class=\"wp-image-1114\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">People<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_network-icon2.png\" alt=\"\" class=\"wp-image-1103\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Network<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_projects-icon2.png\" alt=\"\" class=\"wp-image-1120\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Projects<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Icons_publications-icon2.png\" alt=\"\" class=\"wp-image-2818\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Publications<\/p>\n<\/div>\n<\/div>\n<\/div><button class=\"etb-scroll-button left\" aria-label=\"Scroll to the left\"><span class=\"chevron-left\"><\/span><\/button><button class=\"etb-scroll-button right\" aria-label=\"Scroll to the right\"><span class=\"chevron-right\"><\/span><\/button><\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-contents has-border-color has-accent-6-border-color\" style=\"border-width:1px\">\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">    <div class=\"team-block-page\">\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/images-2-1-300x300.jpg\" class=\" wp-post-image\" alt=\"\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/images-2-1-300x300.jpg 300w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/images-2-1-150x150.jpg 150w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/images-2-1-768x768.jpg 768w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/images-2-1.jpg 1000w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>                <div class=\"team-member-content\">\n                    <h3>Professor Chris Little<\/h3>\n                    <div class=\"team-content\">\n                        \n<p class=\"is-style-text-subtitle\" style=\"font-size:clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.191), 0.98rem);\">Director Raymond Purves Bone and Joint Research Lab<br>Surgery, Faculty of Medicine and Health, Northern Clinical School<\/p>\n\n\n\n<p><\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">    <div class=\"team-block-page\">\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"181\" height=\"233\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Team_Dr-Jiao-Jiao-Li-181x233-1.jpg\" class=\" wp-post-image\" alt=\"Dr Jiao Jiao Li\" \/>                <div class=\"team-member-content\">\n                    <h3>Dr Jiao Jiao Li<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Honorary Associate<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"181\" height=\"232\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Team_Dr-Cindy-Shu-181x232-1.jpg\" class=\" wp-post-image\" alt=\"Dr Cindy Shu\" \/>                <div class=\"team-member-content\">\n                    <h3>Dr Cindy Shu<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Research Fellow<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"180\" height=\"270\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Team_team-Dr-Sanaa-Zaki.jpg\" class=\" wp-post-image\" alt=\"Associate Professor Sanaa Zaki\u00a0\" \/>                <div class=\"team-member-content\">\n                    <h3>Associate Professor Sanaa Zaki\u00a0<\/h3>\n                    <div class=\"team-content\">\n                        \n<p class=\"is-style-text-subtitle\" style=\"font-size:clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.191), 0.98rem);\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-accent-3-color\"><strong>Co-Chair, Neuroscience and Pain<\/strong><\/mark><\/p>\n\n\n\n<p class=\"is-style-text-subtitle\" style=\"font-size:clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.191), 0.98rem);\">Postdoctoral Scientist <br>Raymond Purves Bone and Joint Research<\/p>\n\n\n\n<p class=\"is-style-text-subtitle\" style=\"font-size:clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.191), 0.98rem);\"><br><\/p>\n\n\n\n<p><\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Dr James Melrose<\/h3>\n                    <div class=\"team-content\">\n                        <p>Honorary Senior Research Fellow<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Daniel Burkhardt<\/h3>\n                    <div class=\"team-content\">\n                        <p>Research Officer<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Susan Smith<\/h3>\n                    <div class=\"team-content\">\n                        <p>Technical Officer<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Jiarong (Devina) Li \u2013 PhD Student<\/h3>\n                    <div class=\"team-content\">\n                                            <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Harrison Johansen<\/h3>\n                    <div class=\"team-content\">\n                        <p>Honours Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Kate Hoare<\/h3>\n                    <div class=\"team-content\">\n                        <p>Honours Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Sidharth Aravind<\/h3>\n                    <div class=\"team-content\">\n                        <p>PhD Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Ye (Janey) Zhang<\/h3>\n                    <div class=\"team-content\">\n                        <p>Visiting Researcher<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Roshana Vander Wall<\/h3>\n                    <div class=\"team-content\">\n                        <p>Research Assistant<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Jiaqi (Yancy) Chen<\/h3>\n                    <div class=\"team-content\">\n                        <p>Honours Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Zhiyu Mu<\/h3>\n                    <div class=\"team-content\">\n                        <p>Masters Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Sofia Drakoulis<\/h3>\n                    <div class=\"team-content\">\n                        <p>Honours Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Thai Khang (Ken) Hy<\/h3>\n                    <div class=\"team-content\">\n                        <p>PhD Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Renee Nayager<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Research Student<\/p>\n\n\n\n<p><\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Jasmine Faddis<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Honours Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<p><a href=\"https:\/\/ibjr.sydney.edu.au\" target=\"_blank\" rel=\"noopener\">https:\/\/ibjr.sydney.edu.au<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<p><strong>Developing regenerative therapies for osteoarthritis<\/strong>&nbsp;\u2013 To investigate the interactions between stem cells and diseased joint cells, and build on this knowledge to develop new ways of treating osteoarthritis<\/p>\n\n\n\n<p><strong>Developing new implants for musculoskeletal tissue repair<\/strong>&nbsp;\u2013 To develop and test tissue engineered methods of repairing musculoskeletal tissues including bones and joints<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"c7d8b244-fbe7-4759-928a-3069acc60911\">\n<ol class=\"wp-block-list\">\n<li><a href=\"http:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/christopher.little.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/christopher.little.php#publications-by-year<\/a><\/li>\n\n\n\n<li>Jim Melrose<br><a href=\"http:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/james.melrose.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/james.melrose.php#publications-by-year<\/a><\/li>\n\n\n\n<li>Margaret Smith<br><a href=\"https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/mobsmith.php#publications-by-year%20\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/mobsmith.php#publications-by-year%20<\/a><\/li>\n\n\n\n<li>Jiao Jiao Li<br><a href=\"http:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/jiaojiao.li.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/jiaojiao.li.php#publications-by-year<\/a><\/li>\n\n\n\n<li>Cindy Shu<br><a href=\"https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/cindy.shu.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/cindy.shu.php#publications-by-year<\/a><\/li>\n\n\n\n<li>Sanaa Zaki<br><a href=\"https:\/\/sydney.edu.au\/science\/people\/sanaa.zaki.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/sydney.edu.au\/science\/people\/sanaa.zaki.php#publications-by-year<\/a><\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"featured_media":416,"template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"research-group-tax":[],"primary-research-area":[56],"class_list":["post-2674","research-group","type-research-group","status-publish","has-post-thumbnail","hentry","primary-research-area-musculoskeletal"],"acf":{"team_leads":[3152],"team_members":[3258,3259,3163,3261,3262,3263,3264,3265,3266,3267,3268,3269,3270,3271,3272,3273,4865,5092]},"uagb_featured_image_src":{"full":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves.jpg",2000,590,false],"thumbnail":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves-150x150.jpg",150,150,true],"medium":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves-300x89.jpg",300,89,true],"medium_large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves-768x227.jpg",768,227,true],"large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves-1024x302.jpg",1024,302,true],"1536x1536":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves-1536x453.jpg",1536,453,true],"2048x2048":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Raymond-Purves.jpg",2000,590,false]},"uagb_author_info":{"display_name":"quoc.nguyen4@health.nsw.gov.au","author_link":"https:\/\/kollinginstitute.org.au\/news_demo\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"The Raymond Purves Bone and Joint Research Laboratory leads Australia in research into some of the key musculoskeletal diseases affecting our population. This includes osteoarthritis, tendon injury and intervertebral disc degeneration. There is currently no cure for these common, chronic disabling conditions and long-term management options are limited. 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