{"id":2659,"date":"2025-09-17T15:06:45","date_gmt":"2025-09-17T05:06:45","guid":{"rendered":"https:\/\/webdev.sydney.edu.au\/kolling\/research-group\/dermatology\/"},"modified":"2026-07-31T10:26:54","modified_gmt":"2026-07-31T00:26:54","slug":"dermatology","status":"publish","type":"research-group","link":"https:\/\/kollinginstitute.org.au\/news_demo\/research-group\/dermatology\/","title":{"rendered":"Dermatology"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull has-white-background-color has-background is-layout-flow wp-block-group-is-layout-flow\" style=\"padding-top:0;padding-bottom:0\">\n<div style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0;--etb-a-tab-btn-bg-color:#007ed5;--etb-a-tab-btn-text-color:#FBFAF3;--etb-a-tab-btn-heading-color:#FFFFFF;--etb-a-tab-image-filter:none;--etb-a-tab-bt-style:none;--etb-a-tab-bt-width:0px;--etb-a-tab-br-style:none;--etb-a-tab-br-width:0px;--etb-a-tab-bb-style:none;--etb-a-tab-bb-width:0px;--etb-a-tab-bl-style:none;--etb-a-tab-bl-width:0px;--etb-h-tab-btn-bg-color:color-mix(in srgb, currentColor 20%, transparent);--etb-h-tab-btn-text-color:#FBFAF3;--etb-h-tab-image-filter:none;--etb-h-tab-bb-color:#ab40a1;--etb-h-tab-bb-width:2px\" class=\"wp-block-easy-tabs-block-tabs has-active-etb-bg-color has-active-etb-text-color has-active-etb-heading-color has-active-etb-border has-active-etb-duotone has-hover-etb-bg-color has-hover-etb-text-color has-hover-etb-border  false\" data-id=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" data-initial-tab=\"1\" data-trigger=\"click\" data-accessibility=\"true\"><div class=\"wp-block-easy-tabs-block-tabs-inner is-layout-flow wp-block-easy-tabs-block-tabs-is-layout-flow\">\n<div class=\"etb-tabs-buttons-scrollable-with-arrows wp-container-content-9cfa9a5a\"><div class=\"wp-block-easy-tabs-block-tab-buttons has-etb-buttons-scrollable has-small-font-size is-content-justification-left is-layout-flex wp-container-easy-tabs-block-tab-buttons-is-layout-1a549490 wp-block-easy-tabs-block-tab-buttons-is-layout-flex\" style=\"border-bottom-color:var(--wp--preset--color--accent-6);border-bottom-width:1px;padding-top:0;padding-bottom:0\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" role=\"tablist\">\n<button class=\"wp-block-easy-tabs-block-tab-button has-text-color has-link-color wp-elements-29bc920b546c3ab7d32a99fcb9dae9d4\" style=\"color:#101827\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"4e2e1331-aeba-43aa-9a7c-07a74e2c1017\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab-4e2e1331-aeba-43aa-9a7c-07a74e2c1017\" tabindex=\"-1\">\n<h2 class=\"wp-block-heading has-contrast-color has-text-color has-link-color has-medium-font-size wp-elements-ff56fb5b180573e3245b4ec13836c990\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0\">About us<\/h2>\n<\/button>\n\n\n\n<button class=\"wp-block-easy-tabs-block-tab-button has-contrast-color has-text-color has-link-color wp-elements-dcc3457aeecf2e9ca09c8535d583598f\" style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.185), 16px);font-style:normal;font-weight:600;line-height:1.5\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"64049a74-c3ff-46b3-bedc-3776ee0c7a98\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab-64049a74-c3ff-46b3-bedc-3776ee0c7a98\" tabindex=\"-1\">\n<h2 class=\"wp-block-heading has-medium-font-size\">Our Team<\/h2>\n<\/button>\n\n\n\n<button class=\"wp-block-easy-tabs-block-tab-button has-contrast-color has-text-color has-link-color wp-elements-64c179bfd75c2c242877d5ec0bfaaf5c\" style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.185), 16px);font-style:normal;font-weight:600;line-height:1.5\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"1fb17064-c4f9-417c-9167-cad2cd809405\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab-1fb17064-c4f9-417c-9167-cad2cd809405\" tabindex=\"-1\">\n<h2 class=\"wp-block-heading has-medium-font-size\">Projects<\/h2>\n<\/button>\n\n\n\n<button class=\"wp-block-easy-tabs-block-tab-button has-contrast-color has-text-color has-link-color wp-elements-2a04e1155ccf1b47fface626d048177f\" style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.185), 16px);font-style:normal;font-weight:600;line-height:1.5\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"ccc9bc85-4d23-4587-8721-8b49636b3c9d\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab-ccc9bc85-4d23-4587-8721-8b49636b3c9d\" tabindex=\"-1\">\n<h2 class=\"wp-block-heading has-medium-font-size\">Clinical Trials<\/h2>\n<\/button>\n\n\n\n<button class=\"wp-block-easy-tabs-block-tab-button has-text-color has-link-color wp-elements-06609eecd1bc75bd1cd96b2c82879793\" style=\"color:#101827\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"b1aa5fd3-9feb-475f-b0d4-e7aa2d858c1f\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab-b1aa5fd3-9feb-475f-b0d4-e7aa2d858c1f\" tabindex=\"-1\">\n<h2 class=\"wp-block-heading has-contrast-color has-text-color has-link-color has-medium-font-size wp-elements-fc8e63bdef8ffff0f650df89bd2e5a68\">Collaborations<\/h2>\n<\/button>\n<\/div><button class=\"etb-scroll-button left\" aria-label=\"Scroll to the left\"><span class=\"chevron-left\"><\/span><\/button><button class=\"etb-scroll-button right\" aria-label=\"Scroll to the right\"><span class=\"chevron-right\"><\/span><\/button><\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-contents\" style=\"border-style:none;border-width:0px\">\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-fade\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"tab-4e2e1331-aeba-43aa-9a7c-07a74e2c1017\" aria-labelledby=\"4e2e1331-aeba-43aa-9a7c-07a74e2c1017\" role=\"tabpanel\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7387b849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-right:var(--wp--preset--spacing--60);flex-basis:70%\">\n<p class=\"wp-block-paragraph\">At the Royal North Shore Hospital Department of Dermatology Clinical and Translational Laboratory, our projects span the breadth and depth of dermatology, from skin cancers to inflammatory dermatoses, from children to adulthood, we explore them all. To do this, we conduct clinical trials, and clinical and translational research projects.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It can take more than 30 years from the discovery of a new medicine in the laboratory to the approved use of that compound with a patient in a clinic. It can then be another decade before that therapeutic is widely adopted by the medical community.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Our research team accelerates this discovery and implementation process in three important ways. Firstly, by being actively involved in clinical trials, we can offer our patients immediate access to the latest and most advanced medicines.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Secondly, we conduct clinical studies to improve our understanding of the use of existing and new medicines, alongside projects to improve the early diagnosis and recognition of diseases.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">And lastly, we carry out laboratory experiments, with a focus on clinical observation and human tissues to better understand the causes of these conditions.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ultimately, this means we are able to contribute to the discovery of new and targeted therapies for dermatological conditions.&nbsp;<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<div class=\"wp-block-cover has-aspect-ratio\" style=\"padding-right:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--60);min-height:30vh;aspect-ratio:1;min-height:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" class=\"wp-block-cover__image-background wp-image-7451 size-full\" alt=\"\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2026\/07\/Kolling-PRA-Tiles_600x600px_Cancer.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2026\/07\/Kolling-PRA-Tiles_600x600px_Cancer.jpg 600w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2026\/07\/Kolling-PRA-Tiles_600x600px_Cancer-300x300.jpg 300w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2026\/07\/Kolling-PRA-Tiles_600x600px_Cancer-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-black-background-color has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-container-core-cover-is-layout-6ad4e947 wp-block-cover-is-layout-constrained\">\n<div class=\"wp-block-group is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-1af4f3bb wp-block-group-is-layout-flex\" style=\"min-height:20vh\">\n<p class=\"has-text-align-center has-base-color has-text-color has-link-color has-lora-font-family wp-elements-a2d8d2e82215a51bc78442d0433c9262 wp-block-paragraph\" style=\"font-size:clamp(18.959px, 1.185rem + ((1vw - 3.2px) * 1.022), 30px);\"><a href=\"https:\/\/kollinginstitute.org.au\/news_demo\/neuroscience-and-pain-research\"><\/a>Cancer<br><a href=\"https:\/\/kollinginstitute.org.au\/news_demo\/neuroscience-and-pain-research\"><\/a><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-916c4c57 wp-block-buttons-is-layout-flex\" style=\"padding-top:0;padding-bottom:0\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-100\"><a class=\"wp-block-button__link has-base-color has-accent-3-background-color has-text-color has-background has-link-color has-border-color has-accent-5-border-color wp-element-button\" href=\"https:\/\/kollinginstitute.org.au\/cancer-research\/\" style=\"border-width:2px;border-radius:30px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--70)\">Find out more<\/a><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-fade\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"tab-64049a74-c3ff-46b3-bedc-3776ee0c7a98\" aria-labelledby=\"64049a74-c3ff-46b3-bedc-3776ee0c7a98\" role=\"tabpanel\">\n<div class=\"wp-block-group has-background has-global-padding is-layout-constrained wp-container-core-group-is-layout-fb7be5c4 wp-block-group-is-layout-constrained\" style=\"background-color:#0000000d;margin-top:var(--wp--preset--spacing--70);margin-bottom:var(--wp--preset--spacing--70);padding-top:var(--wp--preset--spacing--50);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50);padding-left:var(--wp--preset--spacing--50)\">\n<h3 class=\"wp-block-heading has-contrast-color has-text-color has-link-color wp-elements-0df2b60564b8e462012545eec83a1e36\">Team Lead<\/h3>\n\n\n    <div class=\"team-block-page is-single-lead\">\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"180\" height=\"270\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Team_Prof-Gayle-Fischer-OAM.jpg\" class=\" wp-post-image\" alt=\"A\/Prof Gayle Fischer OAM\" \/>                <div class=\"team-member-content\">\n                    \n                    <h3>\n                                                    A\/Prof Gayle Fischer OAM                                            <\/h3>\n\n                    <div class=\"team-content\">\n                        \n<p class=\"wp-block-paragraph\">Associate Professor<br>Dermatology, Northern Clinical School<br>Head of Department<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Professor Gayle Fischer is the Royal North Shore Hospital Head of Department of Dermatology, and an Associate Professor at the University of Sydney, Discipline of Dermatology. Her research interests are vulval disease, paediatric dermatology and medical education. She runs a vulval disease and paediatric dermatology service at Royal North Shore Hospital. She has a 20-year career in researching and publishing on the subject of paediatric and vulval disease.<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading has-accent-4-color has-text-color has-link-color wp-elements-918ab976db889b4c0e449ca011fea44f\">Team Members<\/h3>\n\n\n\n    <div class=\"team-block-page\">\n                    <div class=\"team-member\">\n                <img decoding=\"async\" src=\"https:\/\/kollinginstitute.org.au\/wp-content\/uploads\/2025\/10\/headshot_placeholder.png\" class=\"attachment-medium size-medium\" alt=\"Dr Emma Smith PhD\">                <div class=\"team-member-content\">\n                                        \n                    <h3>\n                                                    Dr Emma Smith PhD                                            <\/h3>\n                    \n                    <div class=\"team-content\">\n                        <p>Clinical Trials Coordinator<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                <img decoding=\"async\" src=\"https:\/\/kollinginstitute.org.au\/wp-content\/uploads\/2025\/10\/headshot_placeholder.png\" class=\"attachment-medium size-medium\" alt=\"Erin Mewton\">                <div class=\"team-member-content\">\n                                        \n                    <h3>\n                                                    Erin Mewton                                            <\/h3>\n                    \n                    <div class=\"team-content\">\n                        <p>Transitional Nurse Practitioner<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                <img decoding=\"async\" src=\"https:\/\/kollinginstitute.org.au\/wp-content\/uploads\/2025\/10\/headshot_placeholder.png\" class=\"attachment-medium size-medium\" alt=\"Helen Sun\">                <div class=\"team-member-content\">\n                                        \n                    <h3>\n                                                    Helen Sun                                            <\/h3>\n                    \n                    <div class=\"team-content\">\n                        <p>Dermatology Research Fellow<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                <img decoding=\"async\" src=\"https:\/\/kollinginstitute.org.au\/wp-content\/uploads\/2025\/10\/headshot_placeholder.png\" class=\"attachment-medium size-medium\" alt=\"Haley Young\">                <div class=\"team-member-content\">\n                                        \n                    <h3>\n                                                    Haley Young                                            <\/h3>\n                    \n                    <div class=\"team-content\">\n                        <p>Clinical Nurse Consultant<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-fade\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"tab-1fb17064-c4f9-417c-9167-cad2cd809405\" aria-labelledby=\"1fb17064-c4f9-417c-9167-cad2cd809405\" role=\"tabpanel\">\n<h3 class=\"wp-block-heading has-contrast-color has-text-color has-link-color wp-elements-ca252d15e049e7d1bfa1ce5066a7ad2c\"><strong>Translational Laboratory:<\/strong>&nbsp;<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A key purpose of the Royal North Shore Hospital Department of Dermatology Clinical and Translational Laboratory is to discover and refine better therapies through clinically relevant laboratory studies. We aim to be the premier laboratory for dermatology translational studies and for dermatologist clinician-scientists to work globally.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We hope that within our lifetimes we will see targeted therapies for all dermatological conditions. We are well placed to achieve this given our talented team, our access to state-of-art equipment within the Kolling Institute and the University of Sydney, and our emphasis on human clinical observation and primary human tissue.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Current Translational Projects:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Cellular and Molecular Pathophysiology of Chronic Vulvovaginal Candidiasis (CVVC).<\/li>\n\n\n\n<li>Targeting EGFR Inhibition for Palmoplantar Keratoderma, Pachyonychia Congenita and Ichthyoses<\/li>\n\n\n\n<li>Cellular and Molecular Mechanisms Underlying Biopsy-Induced Regression of Skin Cancers<\/li>\n\n\n\n<li>Understanding and Targeting the Mucinous and Sclerotic Stroma of Basal Cell Carcinomas with a Novel Laser Wavelength<\/li>\n\n\n\n<li>Optimising Ex-Vivo Confocal Assessment of Tumours for Margin Control<\/li>\n\n\n\n<li>Targeting FGFR3 for Actinic and Seborrhoeic Keratoses<\/li>\n\n\n\n<li>Targeting IGF1R for Acne Conglobata and Fulminans<\/li>\n\n\n\n<li>Improving the Safety and Efficacy of Systemic Acne Therapy through a Novel Sebocyte-Specific Biologic Conjugated Retinoid<\/li>\n\n\n\n<li>Understanding the Immunogenicity of Advanced Therapeutics to Improve their Efficacy and Survival<\/li>\n\n\n\n<li>Utilising Insights from the Endogenous Nuclear Envelope to Develop a Sacrificial Biologics Cellular Sunshield<\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"855\" height=\"415\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_graphic.jpg\" alt=\"\" class=\"wp-image-2944\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_graphic.jpg 855w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_graphic-300x146.jpg 300w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_graphic-768x373.jpg 768w\" sizes=\"auto, (max-width: 855px) 100vw, 855px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">To enquire about any of our existing or upcoming translational research, please contact our Dermatology Research Fellow: <a href=\"mailto:nslhd-dermatologyresearch@health.nsw.gov.au\" target=\"_blank\" rel=\"noreferrer noopener\">nslhd-dermatologyresearch@health.nsw.gov.au<\/a>&nbsp;<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-fade\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"tab-ccc9bc85-4d23-4587-8721-8b49636b3c9d\" aria-labelledby=\"ccc9bc85-4d23-4587-8721-8b49636b3c9d\" role=\"tabpanel\">\n<p class=\"wp-block-paragraph\">Clinical trials conducted at our Royal North Shore Hospital (RNSH) site are part of international multi-centre industry sponsored clinical trials. All the trials aim to bring the latest and most advanced therapies to our patients. We mainly conduct phase 2b and phase 3 clinical trials as we believe these therapies are at a stage that is most beneficial for our patient cohort. To enquire about any of our current or upcoming clinical trials, please contact our Clinical Trials Manager, Dr Emma Smith, PhD: <a href=\"mailto:nslhd-dermatologyresearch@health.nsw.gov.au\" target=\"_blank\" rel=\"noreferrer noopener\">nslhd-dermatologyresearch@health.nsw.gov.au<\/a>&nbsp;<\/p>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: true, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-2&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-2-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" data-wp-on--keydown=\"actions.handleKeyDown\" id=\"accordion-item-2\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><span class=\"wp-block-accordion-heading__toggle-title\">Atopic Dermatitis<\/span><\/button><\/h3>\n\n\n\n<div inert aria-labelledby=\"accordion-item-2\" data-wp-bind--inert=\"!state.isOpen\" id=\"accordion-item-2-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<ul class=\"wp-block-list\">\n<li>A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NKTR-358 (Rezpegaldesleukin) Monotherapy in the Treatment of Patients \u2265 12 Years of Age with Moderate-to-Severe Atopic Dermatitis<\/li>\n\n\n\n<li>A Phase 3, Multicenter, Double-blind Maintenance Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASCEND)<\/li>\n\n\n\n<li>A phase 3 randomized, placebo-controlled, double-blind study to evaluate upadacitinib in combination with topical corticosteroids in adolescent and adult subjects with moderate to severe atopic dermatitis<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" data-wp-on--keydown=\"actions.handleKeyDown\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><span class=\"wp-block-accordion-heading__toggle-title\">Pyoderma GangrenosumAtopic Dermatitis<\/span><\/button><\/h3>\n\n\n\n<div inert aria-labelledby=\"accordion-item-3\" data-wp-bind--inert=\"!state.isOpen\" id=\"accordion-item-3-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">A multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial to evaluate safety and efficacy of spesolimab (BI 655130) in adult patients with ulcerative pyoderma gangrenosum (PG) who require systemic therapy<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-4&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-4-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" data-wp-on--keydown=\"actions.handleKeyDown\" id=\"accordion-item-4\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><span class=\"wp-block-accordion-heading__toggle-title\">Lupus&nbsp;<\/span><\/button><\/h3>\n\n\n\n<div inert aria-labelledby=\"accordion-item-4\" data-wp-bind--inert=\"!state.isOpen\" id=\"accordion-item-4-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">A Phase 3, Randomized, Double-Blind, Placebo-Controlled Parallel Study to Evaluate the Efficacy and Safety of Enpatoran in Participants with Active Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease Receiving Standard of Care<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-5&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-5-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" data-wp-on--keydown=\"actions.handleKeyDown\" id=\"accordion-item-5\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><span class=\"wp-block-accordion-heading__toggle-title\">Vitiligo&nbsp;<\/span><\/button><\/h3>\n\n\n\n<div inert aria-labelledby=\"accordion-item-5\" data-wp-bind--inert=\"!state.isOpen\" id=\"accordion-item-5-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">A Phase 3 Randomized, Double-Blind, 52-Week Placebo-Controlled Multi-Center Study with A Double-Blind 52-Week Extension Period with Randomized Dose Up\/Dose Down Titration Investigating the Efficacy, Safety, and Tolerability of Ritlecitinib in Adult Vitiligo.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1774\" height=\"887\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Jul-31-2026-10_04_01-AM.png\" alt=\"\" class=\"wp-image-7444\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Jul-31-2026-10_04_01-AM.png 1774w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Jul-31-2026-10_04_01-AM-300x150.png 300w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Jul-31-2026-10_04_01-AM-1024x512.png 1024w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Jul-31-2026-10_04_01-AM-768x384.png 768w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Jul-31-2026-10_04_01-AM-1536x768.png 1536w\" sizes=\"auto, (max-width: 1774px) 100vw, 1774px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-fade\" data-selector=\"15dcc441-9734-467a-b5cc-e31f82dca9f0\" id=\"tab-b1aa5fd3-9feb-475f-b0d4-e7aa2d858c1f\" aria-labelledby=\"b1aa5fd3-9feb-475f-b0d4-e7aa2d858c1f\" role=\"tabpanel\">\n<p class=\"wp-block-paragraph\">Our collaborators and research partners are through the industry sponsored clinical trials and the care provided to our patients in the public clinics at Royal North Shore Hospital. To date, we have worked with various sponsors such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>AbbVie Pty Ltd<\/li>\n\n\n\n<li>Amgen Australia Pty Ltd<\/li>\n\n\n\n<li>Boehringer Ingelheim<\/li>\n\n\n\n<li>Ego Pharmaceuticals<\/li>\n\n\n\n<li>La Roche-Posay Australia<\/li>\n\n\n\n<li>Lilly Australia \u2013 Eli Lilly<\/li>\n\n\n\n<li>Merck Healthcare Pty Ltd<\/li>\n\n\n\n<li>Nektar Therapeutics<\/li>\n\n\n\n<li>Pfizer Australia<\/li>\n\n\n\n<li>Sanofi and Regeneron Pharmaceuticals<\/li>\n\n\n\n<li>UCB Australia<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n","protected":false},"featured_media":395,"template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"primary-research-area":[62],"class_list":["post-2659","research-group","type-research-group","status-publish","has-post-thumbnail","hentry","primary-research-area-cancer"],"acf":{"team_leads":[3601],"team_members":[3254,3255,3256,3257]},"uagb_featured_image_src":{"full":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner.jpg",2000,591,false],"thumbnail":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner-150x150.jpg",150,150,true],"medium":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner-300x89.jpg",300,89,true],"medium_large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner-768x227.jpg",768,227,true],"large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner-1024x303.jpg",1024,303,true],"1536x1536":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner-1536x454.jpg",1536,454,true],"2048x2048":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_dermatogoly-banner.jpg",2000,591,false]},"uagb_author_info":{"display_name":"swatee.jain@sydney.edu.au","author_link":"https:\/\/kollinginstitute.org.au\/news_demo\/author\/"},"uagb_comment_info":0,"uagb_excerpt":null,"_links":{"self":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group"}],"about":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/types\/research-group"}],"version-history":[{"count":18,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2659\/revisions"}],"predecessor-version":[{"id":7447,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2659\/revisions\/7447"}],"acf:post":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3257"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3256"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3255"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3254"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3601"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/media\/395"}],"wp:attachment":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/media?parent=2659"}],"wp:term":[{"taxonomy":"primary-research-area","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/primary-research-area?post=2659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}