{"id":2655,"date":"2025-09-17T15:06:45","date_gmt":"2025-09-17T05:06:45","guid":{"rendered":"https:\/\/webdev.sydney.edu.au\/kolling\/research-group\/cardiovascular-and-hormonal-research-laboratory\/"},"modified":"2026-02-19T10:08:30","modified_gmt":"2026-02-18T23:08:30","slug":"cardiovascular-and-hormonal-research-laboratory","status":"publish","type":"research-group","link":"https:\/\/kollinginstitute.org.au\/news_demo\/research-group\/cardiovascular-and-hormonal-research-laboratory\/","title":{"rendered":"Cardiovascular and Hormonal Research Laboratory"},"content":{"rendered":"\n<p>The Cardiovascular and Hormonal Research Laboratory has a clinical and translational research focus. It investigates the sex differences in heart disease, and examines the measurement and management of blood pressure.<\/p>\n\n\n\n<p>The research lab is positioned within the Kolling Institute at Royal North Shore Hospital, ensuring research progress directly influences clinical care. It also ensures patient experiences inform the direction of research activity.<\/p>\n\n\n\n<p>Our current projects target the following research areas:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Understanding how steroid hormone receptors are regulated in the heart<\/li>\n\n\n\n<li>Sex differences in heart disease and hypertension<\/li>\n\n\n\n<li>Accurate measurement of blood pressure by both equipment validation and education<\/li>\n\n\n\n<li>Blood pressure variability and phenotyping hypertension<\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"985\" height=\"693\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Measurement-of-AMBP-for-CHR-Lab-2-.jpg\" alt=\"\" class=\"wp-image-2918\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Measurement-of-AMBP-for-CHR-Lab-2-.jpg 985w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Measurement-of-AMBP-for-CHR-Lab-2--300x211.jpg 300w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Measurement-of-AMBP-for-CHR-Lab-2--768x540.jpg 768w\" sizes=\"auto, (max-width: 985px) 100vw, 985px\" \/><figcaption class=\"wp-element-caption\">Measurement of blood pressure a key priority following &#8220;Global Burden of Disease&#8221;: 2019, Lancet &#8211; systolic BP is the #1 risk factor for death and disability in women.<\/figcaption><\/figure>\n\n\n\n<p>The Cardiovascular and Hormonal Research Laboratory is led by Dr Anastasia Mihailidou.<\/p>\n\n\n\n<p>Dr Mihailidou was recently recognised by the Lancet with her appointment to the Commission on Cardiovascular Disease in Women. Nationally, her work has informed clinical practice through the development of the Australian Guidelines for Ambulatory Blood Pressure Monitoring.<\/p>\n\n\n\n<p>Dr Mihailidou has been part of the select committee preparing an application for a Medicare rebate for ambulatory blood pressure monitoring. The translational focus of the Cardiovascular and Hormonal Research Laboratory has led to both national and international collaborations involving research teams in Egypt, Europe and Hong Kong.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"496\" height=\"398\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_PACE-students-TEAM-1.jpg\" alt=\"\" class=\"wp-image-2919\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_PACE-students-TEAM-1.jpg 496w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_PACE-students-TEAM-1-300x241.jpg 300w\" sizes=\"auto, (max-width: 496px) 100vw, 496px\" \/><figcaption class=\"wp-element-caption\">Bachelor of Clinical Science students from Macquarie University presentations for the Professional and Community\nEngagement (PACE) Activity between Macquarie University and NSLHD.<\/figcaption><\/figure>\n\n\n\n<div style=\"border-style:none;border-width:0px;--etb-a-tab-btn-bg-color:#FFFFFF;--etb-a-tab-btn-text-color:#ab40a1;--etb-a-tab-btn-heading-color:#ffffff;--etb-a-tab-bt-style:none;--etb-a-tab-bt-width:0px;--etb-a-tab-br-style:none;--etb-a-tab-br-width:0px;--etb-a-tab-bb-style:none;--etb-a-tab-bb-width:0px;--etb-a-tab-bl-style:none;--etb-a-tab-bl-width:0px;--etb-h-tab-btn-bg-color:#ffffff;--etb-h-tab-btn-text-color:#000000;--etb-h-tab-btn-heading-color:#000000;--etb-h-tab-bt-style:none;--etb-h-tab-bt-width:0px;--etb-h-tab-br-style:none;--etb-h-tab-br-width:0px;--etb-h-tab-bb-style:none;--etb-h-tab-bb-width:0px;--etb-h-tab-bl-style:none;--etb-h-tab-bl-width:0px;--etb-scroll-arrows-icon-color:#ab40a1\" class=\"wp-block-easy-tabs-block-tabs has-active-etb-bg-color has-active-etb-text-color has-active-etb-heading-color has-active-etb-border has-hover-etb-bg-color has-hover-etb-text-color has-hover-etb-heading-color has-hover-etb-border\" data-id=\"b8bccd40-2380-4014-b9a5-4379af7295dd\" data-initial-tab=\"1\" data-trigger=\"click\"><div class=\"wp-block-easy-tabs-block-tabs-inner is-layout-flow wp-block-easy-tabs-block-tabs-is-layout-flow\">\n<div class=\"etb-tabs-buttons-scrollable-with-arrows\"><div class=\"wp-block-easy-tabs-block-tab-buttons has-etb-buttons-scrollable is-layout-flex wp-container-easy-tabs-block-tab-buttons-is-layout-d7af6e26 wp-block-easy-tabs-block-tab-buttons-is-layout-flex\" style=\"border-style:none;border-width:0px\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_lead-icon2.png\" alt=\"\" class=\"wp-image-1098\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Lead<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_people-icon2.png\" alt=\"\" class=\"wp-image-1114\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">People<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_network-icon2.png\" alt=\"\" class=\"wp-image-1103\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Network<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_projects-icon2.png\" alt=\"\" class=\"wp-image-1120\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Projects<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Icons_publications-icon2.png\" alt=\"\" class=\"wp-image-2818\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Publications<\/p>\n<\/div>\n<\/div>\n<\/div><button class=\"etb-scroll-button left\" aria-label=\"Scroll to the left\"><span class=\"chevron-left\"><\/span><\/button><button class=\"etb-scroll-button right\" aria-label=\"Scroll to the right\"><span class=\"chevron-right\"><\/span><\/button><\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-contents has-border-color has-accent-6-border-color\" style=\"border-width:1px\">\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">    <div class=\"team-block-page\">\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"194\" height=\"300\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/root_Team_Anastasia-Mihailiodu-1--194x300.jpg\" class=\" wp-post-image\" alt=\"Dr Anastasia S Mihailidou PhD FAHA FCSANZ\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/root_Team_Anastasia-Mihailiodu-1--194x300.jpg 194w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/10\/root_Team_Anastasia-Mihailiodu-1-.jpg 587w\" sizes=\"auto, (max-width: 194px) 100vw, 194px\" \/>                <div class=\"team-member-content\">\n                    <h3>Dr Anastasia S Mihailidou PhD FAHA FCSANZ<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Senior Hospital Scientist, Department of Cardiology<br>Royal North Shore Hospital<br>Head, Cardiovascular and Hormonal Research Laboratory, Kolling Institute<br>Honorary Senior Lecturer, Faculty of Medicine and Health<br>Macquarie University<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\"><\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<ul class=\"wp-block-list\">\n<li>Coalition for Access for Non-Communicable Disease Medicines and Products<\/li>\n\n\n\n<li>Commissioner, Lancet Commission on Cardiovascular Disease in Women<\/li>\n\n\n\n<li>Advisory Board of the STRIDE_BP to standardise blood pressure<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<ol class=\"wp-block-list\">\n<li>The MASTER study &#8211; As part of an international collaboration, the study is investigating the treatment for uncontrolled hypertension based on clinic BP compared to out-of-clinic (ambulatory) BP measurement. Working with her Macquarie University colleagues, Dr Mihailidou is the principal investigator for the only Australian site contributing to this important trial.<\/li>\n\n\n\n<li>Complex exercise intervention to normalise blood pressure and its nocturnal dipping in patients with hypertension in Chinese primary care trial. This study is being conducted in collaboration with colleagues in Hong Kong.<\/li>\n\n\n\n<li>Understanding the structure and function interaction of the stress hormone cortisol with the steroid hormone receptors in the heart.<\/li>\n\n\n\n<li>Maintaining accurate blood pressure measurement skills in a health service in association with colleagues in America and Canada.<\/li>\n\n\n\n<li>Collaborating with the Kolling Institute\u2019s Raymond Purves Laboratory, to investigate how osteoarthritis leads to heart disease in women: &#8220;bad knees and broken hearts&#8221;.<\/li>\n<\/ol>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"b8bccd40-2380-4014-b9a5-4379af7295dd\">\n<p><a href=\"https:\/\/orcid.org\/0000-0001-6435-0411\" target=\"_blank\" rel=\"noreferrer noopener\">Via ORCHID<\/a><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"featured_media":384,"template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"research-group-tax":[],"primary-research-area":[58],"class_list":["post-2655","research-group","type-research-group","status-publish","has-post-thumbnail","hentry","primary-research-area-cardiovascular-and-renal"],"acf":{"team_leads":[3709],"team_members":""},"uagb_featured_image_src":{"full":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery.jpg",2000,591,false],"thumbnail":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-150x150.jpg",150,150,true],"medium":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-300x89.jpg",300,89,true],"medium_large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-768x227.jpg",768,227,true],"large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-1024x303.jpg",1024,303,true],"1536x1536":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-1536x454.jpg",1536,454,true],"2048x2048":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery.jpg",2000,591,false]},"uagb_author_info":{"display_name":"ict-wordpress-support@sydney.edu.au","author_link":"https:\/\/kollinginstitute.org.au\/news_demo\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"The Cardiovascular and Hormonal Research Laboratory has a clinical and translational research focus. It investigates the sex differences in heart disease, and examines the measurement and management of blood pressure. The research lab is positioned within the Kolling Institute at Royal North Shore Hospital, ensuring research progress directly influences clinical care. It also ensures patient&hellip;","_links":{"self":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group"}],"about":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/types\/research-group"}],"version-history":[{"count":1,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2655\/revisions"}],"predecessor-version":[{"id":4939,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2655\/revisions\/4939"}],"acf:post":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/media\/384"}],"wp:attachment":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/media?parent=2655"}],"wp:term":[{"taxonomy":"research-group-tax","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group-tax?post=2655"},{"taxonomy":"primary-research-area","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/primary-research-area?post=2655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}