{"id":2654,"date":"2025-09-17T15:06:45","date_gmt":"2025-09-17T05:06:45","guid":{"rendered":"https:\/\/webdev.sydney.edu.au\/kolling\/research-group\/cardiac-membrane-biology-laboratory\/"},"modified":"2026-02-19T10:08:06","modified_gmt":"2026-02-18T23:08:06","slug":"cardiac-membrane-biology-laboratory","status":"publish","type":"research-group","link":"https:\/\/kollinginstitute.org.au\/news_demo\/research-group\/cardiac-membrane-biology-laboratory\/","title":{"rendered":"Cardiac Membrane Biology Laboratory"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<p>The Cardiac Membrane Biology Laboratory aims to improve the lives of people suffering cardiac related health issues.<\/p>\n\n\n\n<p>Our research focuses on one of the body\u2019s most crucial molecules \u2013 a molecule which is vital for the contraction of heart cells and therefore the pumping of the heart. As we develop a better understanding of this molecule through laboratory-based experiments, we explore treatments for heart failure, irregular heartbeat and heart damage following cancer treatment.<\/p>\n\n\n\n<p>Our laboratory-based research has led to the discovery of a new potential treatment for heart failure. We are about to begin a clinical trial of this approach with our collaborators based in Denmark.<\/p>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-cf7d2537 default uagb-is-root-container\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<figure class=\"wp-block-image alignleft size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"752\" height=\"1024\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Helge-Lab-Shots-752x1024.jpg\" alt=\"\" class=\"wp-image-2906\" style=\"width:300px\" srcset=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Helge-Lab-Shots-752x1024.jpg 752w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Helge-Lab-Shots-220x300.jpg 220w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Helge-Lab-Shots-768x1045.jpg 768w, https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Content_Helge-Lab-Shots.jpg 961w\" sizes=\"auto, (max-width: 752px) 100vw, 752px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div style=\"border-style:none;border-width:0px;--etb-a-tab-btn-bg-color:#FFFFFF;--etb-a-tab-btn-text-color:#ab40a1;--etb-a-tab-btn-heading-color:#ffffff;--etb-a-tab-bt-style:none;--etb-a-tab-bt-width:0px;--etb-a-tab-br-style:none;--etb-a-tab-br-width:0px;--etb-a-tab-bb-style:none;--etb-a-tab-bb-width:0px;--etb-a-tab-bl-style:none;--etb-a-tab-bl-width:0px;--etb-h-tab-btn-bg-color:#ffffff;--etb-h-tab-btn-text-color:#000000;--etb-h-tab-btn-heading-color:#000000;--etb-h-tab-bt-style:none;--etb-h-tab-bt-width:0px;--etb-h-tab-br-style:none;--etb-h-tab-br-width:0px;--etb-h-tab-bb-style:none;--etb-h-tab-bb-width:0px;--etb-h-tab-bl-style:none;--etb-h-tab-bl-width:0px;--etb-scroll-arrows-icon-color:#ab40a1\" class=\"wp-block-easy-tabs-block-tabs has-active-etb-bg-color has-active-etb-text-color has-active-etb-heading-color has-active-etb-border has-hover-etb-bg-color has-hover-etb-text-color has-hover-etb-heading-color has-hover-etb-border\" data-id=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\" data-initial-tab=\"1\" data-trigger=\"click\"><div class=\"wp-block-easy-tabs-block-tabs-inner is-layout-flow wp-block-easy-tabs-block-tabs-is-layout-flow\">\n<div class=\"etb-tabs-buttons-scrollable-with-arrows\"><div class=\"wp-block-easy-tabs-block-tab-buttons has-etb-buttons-scrollable is-layout-flex wp-container-easy-tabs-block-tab-buttons-is-layout-d7af6e26 wp-block-easy-tabs-block-tab-buttons-is-layout-flex\" style=\"border-style:none;border-width:0px\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_lead-icon2.png\" alt=\"\" class=\"wp-image-1098\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Lead<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_people-icon2.png\" alt=\"\" class=\"wp-image-1114\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"border-style:none;border-width:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">People<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Icons_projects-icon2.png\" alt=\"\" class=\"wp-image-1120\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Projects<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-button\" style=\"border-style:none;border-width:0px\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-6c531013 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"43\" height=\"39\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/09\/root_Icons_publications-icon2.png\" alt=\"\" class=\"wp-image-2818\" style=\"width:20px\"\/><\/figure>\n\n\n\n<p style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">Publications<\/p>\n<\/div>\n<\/div>\n<\/div><button class=\"etb-scroll-button left\" aria-label=\"Scroll to the left\"><span class=\"chevron-left\"><\/span><\/button><button class=\"etb-scroll-button right\" aria-label=\"Scroll to the right\"><span class=\"chevron-right\"><\/span><\/button><\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-contents has-border-color has-accent-6-border-color\" style=\"border-width:1px\">\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">    <div class=\"team-block-page\">\n                    <div class=\"team-member\">\n                <img loading=\"lazy\" decoding=\"async\" width=\"180\" height=\"270\" src=\"https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/08\/Team_Helge-Headshot.jpg\" class=\" wp-post-image\" alt=\"Prof Helge Rasmussen\" \/>                <div class=\"team-member-content\">\n                    <h3>Prof Helge Rasmussen<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Chair of Cardiology<br>Medicine, Northern Clinical School<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">    <div class=\"team-block-page\">\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Dr Chia-Chi Liu<\/h3>\n                    <div class=\"team-content\">\n                        <p>Honorary Senior Research Fellow<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Bei Xu \u2013 Research Assistant<\/h3>\n                    <div class=\"team-content\">\n                                            <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Gideon Jacque<\/h3>\n                    <div class=\"team-content\">\n                        <p>Research Assistant<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Grace Marks<\/h3>\n                    <div class=\"team-content\">\n                        <p>MD Research Project Student<\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n                    <div class=\"team-member\">\n                                <div class=\"team-member-content\">\n                    <h3>Sergey Tumanov<\/h3>\n                    <div class=\"team-content\">\n                        \n<p>Visiting Researcher<\/p>\n\n\n\n<p><\/p>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<h4 class=\"wp-block-heading\">PREVENTION OF CARDIAC SIDE EFFECTS OF CANCER TREATMENT<\/h4>\n\n\n\n<p>This project will investigate a new drug combination therapy that has potential benefits in cancer treatment induced heart failure by targeting the sodium\/potassium pump function.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">A NEW DRUG COMBINATION THERAPY FOR HEART FAILURE<\/h4>\n\n\n\n<p>This project will investigate a drug combination therapy that has potential benefits in heart failure treatment by targeting the sodium\/potassium pump function.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-easy-tabs-block-tab-content etb-animation-slide-up\" data-selector=\"3c2a3b5a-1202-4313-9e91-0f0eee280e20\">\n<ul class=\"wp-block-list\">\n<li>Helge Rasmussen<br><a href=\"https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/helge.rasmussen.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/helge.rasmussen.php#publications-by-year<\/a><br><\/li>\n\n\n\n<li>Elisha Hamilton<br><a href=\"https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/elisha.hamilton.php#publications-by-year\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/sydney.edu.au\/medicine\/people\/academics\/profiles\/elisha.hamilton.php#publications-by-year<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"featured_media":384,"template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"research-group-tax":[],"primary-research-area":[58],"class_list":["post-2654","research-group","type-research-group","status-publish","has-post-thumbnail","hentry","primary-research-area-cardiovascular-and-renal"],"acf":{"team_leads":[3706],"team_members":[3473,3474,3475,3476,4863]},"uagb_featured_image_src":{"full":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery.jpg",2000,591,false],"thumbnail":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-150x150.jpg",150,150,true],"medium":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-300x89.jpg",300,89,true],"medium_large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-768x227.jpg",768,227,true],"large":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-1024x303.jpg",1024,303,true],"1536x1536":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery-1536x454.jpg",1536,454,true],"2048x2048":["https:\/\/kollinginstitute.org.au\/news_demo\/wp-content\/uploads\/2025\/07\/root_Banners_Banner-Cardiology-Discovery.jpg",2000,591,false]},"uagb_author_info":{"display_name":"ict-wordpress-support@sydney.edu.au","author_link":"https:\/\/kollinginstitute.org.au\/news_demo\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"The Cardiac Membrane Biology Laboratory aims to improve the lives of people suffering cardiac related health issues. Our research focuses on one of the body\u2019s most crucial molecules \u2013 a molecule which is vital for the contraction of heart cells and therefore the pumping of the heart. As we develop a better understanding of this&hellip;","_links":{"self":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group"}],"about":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/types\/research-group"}],"version-history":[{"count":3,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2654\/revisions"}],"predecessor-version":[{"id":4938,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group\/2654\/revisions\/4938"}],"acf:post":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/4863"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3476"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3475"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3474"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3473"},{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/team-members\/3706"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/media\/384"}],"wp:attachment":[{"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/media?parent=2654"}],"wp:term":[{"taxonomy":"research-group-tax","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/research-group-tax?post=2654"},{"taxonomy":"primary-research-area","embeddable":true,"href":"https:\/\/kollinginstitute.org.au\/news_demo\/wp-json\/wp\/v2\/primary-research-area?post=2654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}